Last edited by Kazratilar
Saturday, August 1, 2020 | History

6 edition of The Use of Nonhuman Primates in Cardiovascular Disease found in the catalog.

The Use of Nonhuman Primates in Cardiovascular Disease

by S. S. Kalter

  • 29 Want to read
  • 18 Currently reading

Published by Univ of Texas Pr .
Written in English

    Subjects:
  • Mathematics and Science,
  • Science/Mathematics

  • The Physical Object
    FormatHardcover
    Number of Pages480
    ID Numbers
    Open LibraryOL10294151M
    ISBN 100292785100
    ISBN 109780292785106

    Use and Importance of Nonhuman Primates in Metabolic Disease Research: CurrentState of the Field. ILAR J. Dec 1;58(2) doi: /ilar/ilx Kjaergaard M, Nilsson C, Secher A, Kildegaard J, Skovgaard T, Nielsen MO, Grove K, Raun K. The Pocket Handbook of Nonhuman Primate Clinical Medicine is a convenient, concise, case-based handbook written by and for clinicians in charge of the diagnosis and treatment of nonhuman primate patients. Available in both print and electronic formats, this handbook saves readers from having to wade through pages of data and case studies to 5/5(1).

    In addition, 47 percent of nonhuman primates, s individuals, were subjected to painful and distressful experiments in Primates are increasingly used in pharmaceutical and bioterrorism experiments, and researchers continue to promote the “development of a portfolio of non-human primate models for a variety of human diseases and.   Before pharmaceuticals reach the consumer, their safety has to be tested on humans during clinical trials. Preliminary experiments on animals – often rats and dogs – are intended to protect the health of people taking part in these trials. Only few candidate pharmaceuticals are actually tested on non-human primates (NHPs). Primates are needed to .

      CR also reduces the incidence of age-related cancer, cardiovascular disease and immune deficiencies in rodents and in non-human primates 4,15,16,17,18, So, we infer that physiological changes Cited by: Claims can be as vague as: “Nonhuman primates have a unique position in biomedical research related to their close phylogenetic proximity to humans. This close proximity often serves as the basis for scientific justification of their use in research” (9); and, with regard to neuroscience, “Neuroscience is an area in which research with.


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The Use of Nonhuman Primates in Cardiovascular Disease by S. S. Kalter Download PDF EPUB FB2

The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science.

By covering important topics such as study planning and conduct, inter-species genetic drift. Cardiovascular Disease Models in NHPs. Although many aspects of human disease are investigated using NHP disease models (reviewed in Chap.

13, “The Nonhuman Primate Models of Human Disease”), research in the cardiovascular field, particularly diabetes and atherosclerosis, has advanced through the use of NHP models [, ].Author: Jonathan R.

Heyen, Hugo The Use of Nonhuman Primates in Cardiovascular Disease book. Vargas. The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research.

The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management.

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research.

The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary. The Use of Nonhuman Primates in Cardiovascular Safety Assessment a growing use of nonhuman primates in safety assessment testing for new.

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research.

The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary Pages: The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science.

By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal. The book is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and any other persons involved in developing or implementing an OHSP in settings with nonhuman primates (4).

It should be informative for a wide audience, including animal handlers, infectious disease physicians, public health and other. A number of herpesviruses affect nonhuman primates; many exist as latent or subclinical infections in reservoir hosts but cause severe disease or death when transmitted naturally to other hosts.

All macaques are considered to be potential shedders of Cercopithecine herpesvirus type 1 (Herpesvirus simiae, B virus). Nonhuman primates (NHP) remain key animal models for specific types of biomedical research because of their close phylogenetic relationships and physiologic similarities to humans.

1, 8, 10, 12, 18 However, the use of NHP in research has become increasingly controversial such that ensuring a stable supply of NHP to meet biomedical research needs continues to be a Cited by: The use of these measurements for pre-clinical assessment of drug cardiovascular safety and efficacy in non-human primates (NHPs) may promote.

Dahlmann and K. Sewald: Use of nonhuman primates in obstructive lung disease research – is it required. (a) (b) (c) (d) Figure 1. Nonhuman primates used in obstructive lung disease research. Rhesus macaques (Macaca mulatta) (a) and cynomolgus macaques (Macaca fascicularis) (b) belong to the family of old world monkeys (a, b).Author: Franziska Dahlmann, Franziska Dahlmann, Katherina Sewald.

His research and teaching interests include the evolution of social complexity in human and primate societies, conflict negotiation across primates, including humans, and reproductive behavior and ecology. He is also interested in issues of human-nonhuman primate interactions, disease and pathogen by:   Abstract.

The use of non-human primates in biomedical research is a contentious issue that raises serious ethical and practical concerns. In the European Union, where regulations on their use are very tight, the number of non-human primates used in research has been in decline over the past by: In this review, the contribution of nonhuman primates to atherosclerosis research will be discussed, as will the development of atherosclerosis in both human and nonhuman primates.

In addition, a role for age-related conditions in atherosclerosis development in both human and nonhuman primates will be by: The bacteria most commonly associated with GI disease in nonhuman primates are Campylobacter jejuni and Shigella onally, enterotoxigenic Escherichia coli, Pseudomonas aeruginosa, Yersinia spp, Lawsonia intracellularis, Salmonella spp, Aerobacter aerogenes, and Aerobacter hydrophila are implicated.

Nonhuman primates may be. With the new edition of the Guide to the Care and Use of Laboratory Animals (National Research Council ), there has been an increased emphasis on social housing laboratory primates. However, social housing can result in aggression and injury if the partners are not by:   The critical role of nonhuman primates in medical research By Nancy Haigwood Ma Portland, Ore.

Nancy Haigwood, Ph.D., is director of the Oregon National Primate Research Center and a professor of pathobiology and Immunology in the OHSU School of Medicine.(OHSU/John Valls).

My presentation will focus on the use and numbers of nonhuman primates (NHP) in research in the United States. To determine these numbers it was necessary to visit a lot of regulatory agencies—including the CDC, USDA, and NCRR/NIH (for chimpanzee data)—and Indonesia.

The bottom line is that it. Primates--refers here only to nonhuman primates. In certain cases more than one common name, or more than one scientific name, are in current use for a given species.

Some synonyms are indicated by footnotes in Appendix I. Additional examples include the following: 1. The conditions for tool use in primates: implications for the evolution of material culture In order to identify the conditions that favored the flourishing of primate tool use into hominid technology, we examine inter- and intraspecific variation in manufacture and use of tools in extant nonhuman primates, and develop a model to account for.Get this from a library!

Nonhuman Primates in Biomedical Research: Diseases. [Christian R Abee; Keith Mansfield; Suzette D Tardif; Timothy Morris] -- The second edition of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research.of primates, and to suggest ways in which the scientific community might approach the issue (Fig.

1). DISEASE AND PRIMATE POPULATION DYNAMICS A fundamental issue in ecology is determining the factors that regulate the density of animal populations.

TABLE 1. PARASITES EXCHANGED BETWEEN HUMANS AND NONHUMAN PRIMATES: THE ROUTE AND .